Nanotechnology Allows Use of Toxin from Rattlesnake Venom to Manage Neuropathic Pain. A New Study Reported this.

On November 20, 2019, a novel study published in the journal Toxins found that Crotoxin (CTX), encapsulated in nanostructured SBA-15 silica, can induce long-last analgesic effect in the neuropathic pain model in mice.

CTX is extracted from the venom of the South American rattlesnake Crotalus durissus terrificus. Although CTX is well known for its potent analgesic effect, the toxicity of CTX limits its medicinal use. If CTX is encapsulated in nanostructured SBA-15 silica, its toxicity can be reduced and therapeutic effects can be also enhanced.

These data underscore the potential use of the CTX:SBA-15 complex for neuropathic pain control and confirm the protective potential of SBA-15.



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