Using Two Antibiotics to Treat MRSA Infections May Add Nothing! A New Study Suggests This.

Methicillin-resistant staphylococcus aureus (MRSA) is a common and very serious cause of infection. MRSA is tough to treat because it is resistant to many commonly used antibiotics.

On February 11, 2020, a new study published in JAMA found that the addition of 7 days of an antistaphylococcal β-lactam (flucloxacillin, cloxacillin, or cefazolin) to standard antibiotic therapy (vancomycin or daptomycin) did not lead to significant improvement in the primary composite end point of mortality, persistent bacteremia, relapse, or treatment failure in adults with MRSA bacteremia.

This study showed that there is no advantage in using two antibiotics (antistaphylococcal β-lactam plus standard antibiotic therapy) to treat MRSA infections.



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