A Big Step to Identify Drug Candidates against COVID-19

Groundbreaking research published in Nature on April 30, 2020, found 66 druggable human proteins or host factors. 69 molecules potentially target these factors: 29 FDA-approved medications, 12 clinical trial pharmaceuticals, and 28 experimental compounds. Researchers tested a selection of these compounds in various viral tests and discovered two types of pharmacological drugs with antiviral activity: mRNA translation inhibitors and anticipated regulators of the Sigma1 and Sigma2 receptors.

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